Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90289 | 0.94 | REN (0.65) | RENKCNH2 | |
| SCHEMBL89882 | 0.94 | REN (0.64) | RENKCNH2 | |
| SCHEMBL90282 | 0.93 | REN (0.64) | RENKCNH2 | |
| SCHEMBL89385 | 0.89 | REN (0.74) | RENKCNH2 | |
| SCHEMBL1911413 | 0.89 | REN (0.74) | RENKCNH2 | |
| SCHEMBL90716 | 0.87 | REN (0.55) | RENKCNH2 | |
| SCHEMBL89844 | 0.86 | REN (0.55) | RENKCNH2 | |
| SCHEMBL8235848 | 0.86 | REN (0.54) | RENKCNH2 | |
| SCHEMBL90342 | 0.86 | REN (1.00) | RENKCNH2 | |
| SCHEMBL89890 | 0.85 | REN (0.53) | RENKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129411-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-03-06 | — | — | US | disclosed |
| US-20090192148-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192148-A1 | Organic Compounds | REN, ACE, AGTR1 | REN 1/4885KCNH2 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.