Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992732 | 0.80 | BRD4 (0.40) | AOC3L3MBTL1CASRPKMCHRM2 | |
| SCHEMBL2093768 | 0.75 | AOC3 (0.59) | AOC3L3MBTL1CASRPKMTSHR | |
| SCHEMBL8992789 | 0.75 | TACR1 (0.40) | BRD4 | |
| SCHEMBL8993113 | 0.73 | CASR (0.51) | AOC3L3MBTL1CASRMEN1KMT2A | |
| SCHEMBL8756705 | 0.72 | AOC3 (0.49) | AOC3L3MBTL1CASRPKMMAPK1 | |
| SCHEMBL96382 | 0.72 | TAAR1 (0.60) | AOC3CHRM2CHRM1CHRM3MAOB | |
| SCHEMBL29587500 | 0.72 | TAAR1 (0.60) | AOC3CHRM2CHRM1CHRM3MAOB | |
| SCHEMBL8189368 | 0.71 | MAOB (0.47) | CASRMAOB | |
| SCHEMBL4822561 | 0.71 | AOC3 (0.54) | AOC3L3MBTL1PKMTSHRMAPK1 | |
| SCHEMBL477338 | 0.71 | AOC3 (0.54) | AOC3L3MBTL1CASRPKMCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |