Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993104 | 0.88 | IDO1 (0.35) | ALOX5IDO1CASR | |
| SCHEMBL8993000 | 0.84 | L3MBTL1 (0.35) | L3MBTL1FFAR1 | |
| SCHEMBL8992895 | 0.80 | AOC3 (0.45) | BRD4AOC3PKML3MBTL1CASR | |
| SCHEMBL15778630 | 0.77 | IDO1 (0.60) | IDO1AGXTMAOBCHRM2CHRM1 | |
| SCHEMBL8992789 | 0.76 | TACR1 (0.40) | BRD4FFAR1 | |
| SCHEMBL8992799 | 0.75 | IDO1 (0.46) | IDO1AGXTMAOBCHRM2CHRM1 | |
| SCHEMBL12191689 | 0.70 | CRHBP (0.41) | MAOB | |
| SCHEMBL8136938 | 0.70 | LMNA (0.41) | FFAR1 | |
| SCHEMBL480243 | 0.70 | FFAR1 (0.37) | BRD4ALOX5FFAR1MAOB | |
| SCHEMBL480241 | 0.70 | FFAR1 (0.37) | BRD4ALOX5FFAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |