Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1773407 | 0.85 | LOXL2 (0.53) | MAPTRAB9AL3MBTL1LMNAMEN1 | |
| SCHEMBL70372 | 0.85 | TSHR (0.57) | MAPTRAB9AL3MBTL1LMNALOXL2 | |
| SCHEMBL2579068 | 0.85 | KEAP1 (0.56) | MAPTRAB9ALMNAALOX12LOXL2 | |
| SCHEMBL9233909 | 0.84 | LOXL2 (0.51) | MAPTRAB9AL3MBTL1LMNAMEN1 | |
| SCHEMBL305693 | 0.84 | LOXL2 (0.56) | MAPTRAB9AL3MBTL1LMNAKMT2A | |
| SCHEMBL9234838 | 0.84 | RAB9A (0.52) | MAPTRAB9AL3MBTL1LMNALOXL2 | |
| SCHEMBL1773348 | 0.84 | LOXL2 (0.51) | MAPTRAB9AL3MBTL1LMNALOXL2 | |
| SCHEMBL6158387 | 0.82 | TSHR (0.67) | MAPTRAB9AL3MBTL1LMNALOXL2 | |
| SCHEMBL69454 | 0.82 | LOXL2 (0.70) | MAPTMEN1KMT2ALOXL2TSHR | |
| SCHEMBL8561229 | 0.81 | TSHR (0.53) | MAPTRAB9AL3MBTL1LMNALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548269-A | Preparation method of diarylmethane structure compound | 兰州大学 | 2020-08-18 | — | — | CN | disclosed |
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |