Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993326 | 0.91 | HSD17B2 (0.59) | HSD17B2KMT2AMEN1LMNAMAPT | |
| SCHEMBL11458535 | 0.83 | KMT2A (0.63) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL8993227 | 0.82 | HSD17B2 (0.58) | HSD17B2KMT2AMEN1LMNAMAPT | |
| SCHEMBL8992779 | 0.81 | HSD17B2 (0.61) | HSD17B2KMT2AMEN1LMNAMAPT | |
| SCHEMBL9356016 | 0.81 | SMN1; SMN2 (0.60) | HSD17B2KMT2ALMNAMAPTHTT | |
| SCHEMBL14582858 | 0.80 | HSD17B2 (0.68) | HSD17B2KMT2AMEN1LMNAMAPT | |
| SCHEMBL5161173 | 0.79 | HSD17B2 (0.66) | HSD17B2KMT2AMEN1LMNAMAPT | |
| SCHEMBL12968393 | 0.79 | MAOB (0.58) | HSD17B2KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL27845077 | 0.78 | CYP4F2 (0.57) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL14366059 | 0.78 | ALDH1A1 (0.54) | KMT2AMEN1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |