Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51251 | 0.79 | TSHR (0.48) | TSHRALDH1A1CFTRHSD17B10RAB9A | |
| SCHEMBL295086 | 0.79 | GAA (0.42) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4904390 | 0.79 | GAA (0.39) | CTSDALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL1444015 | 0.78 | ALOX15 (0.41) | TSHRALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL18301294 | 0.78 | — | — | |
| SCHEMBL224092 | 0.76 | HDAC8 (0.46) | HSD17B10SMN1; SMN2LMNAKDM4EKMT2A | |
| SCHEMBL1416190 | 0.76 | HPGD (0.53) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1903196 | 0.76 | KMT2A (0.34) | TSHRALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL97054 | 0.74 | KMT2A (0.43) | TSHRALDH1A1HSD17B10NPC1LMNA | |
| SCHEMBL17979561 | 0.74 | RAB9A (0.34) | NPC1RAB9AKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068295-B1 | A NEW HERBICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE | A. Nattermann & Cie. GmbH (DE) | 1985-08-28 | — | — | EP | claimed |
| EP-0602478-B1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-31 | — | — | EP | disclosed |
| US-5453497-A | Process for producing N4 -acyl-5'-deoxy-5-fluorocytidine compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0602478-A1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| EP-0068295-A1 | A new herbicidal composition, processes for its production and its use | A. Nattermann & Cie. GmbH (DE) | 1983-01-05 | — | — | EP | disclosed |