Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993101 | 0.87 | TTR (0.50) | TTRCNR2GAAMAPTTSHR | |
| SCHEMBL8992924 | 0.83 | CNR2 (0.45) | CNR2GAAMAPTTSHRMAPK1 | |
| SCHEMBL8993260 | 0.83 | TTR (0.50) | TTRCNR2GAAMAPTTSHR | |
| SCHEMBL8993322 | 0.80 | CNR2 (0.45) | CNR2GAAMAPTTSHRMAPK1 | |
| SCHEMBL31173715 | 0.79 | TTR (0.50) | TTR | |
| SCHEMBL8231041 | 0.77 | TTR (0.50) | TTRGAAMAPTTSHRMAPK1 | |
| SCHEMBL11838721 | 0.77 | CA2 (0.61) | TTRGAAMAPTTSHRMAPK1 | |
| SCHEMBL3901814 | 0.75 | TTR (0.47) | TTRCA2HTR2A | |
| SCHEMBL5366841 | 0.74 | TTR (0.54) | TTRGAAMAPTTSHRMAPK1 | |
| SCHEMBL9023705 | 0.74 | ACHE (0.56) | GAAMAPTTSHRMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |