Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992888 | 0.85 | MEN1 (0.44) | CNR2GAAMAPTTSHRMAPK1 | |
| SCHEMBL8993206 | 0.83 | TTR (0.46) | TTRCNR2GAAMAPTTSHR | |
| SCHEMBL8993391 | 0.81 | CNR2 (0.44) | CNR2GAAMAPTTSHRMAPK1 | |
| SCHEMBL22800044 | 0.80 | CA2 (0.52) | CNR2GAAMAPTTSHRMAPK1 | |
| SCHEMBL8993101 | 0.80 | TTR (0.50) | TTRCNR2GAAMAPTTSHR | |
| SCHEMBL31173715 | 0.78 | TTR (0.50) | TTR | |
| SCHEMBL8035410 | 0.78 | CNR2 (0.55) | CNR2GAAMAPTGPR55CNR1 | |
| SCHEMBL8993251 | 0.76 | LTA4H (0.46) | MAPTPOLB | |
| SCHEMBL13882403 | 0.75 | TTR (0.43) | TTRCNR2GAAMAPTTSHR | |
| SCHEMBL27469497 | 0.75 | HTR1A (0.50) | TTRGAAMAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |