Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30633032 | 1.00 | S100A4 (0.41) | S100A4HTR2CHTR2BHTR2AADRB1 | |
| SCHEMBL25124805 | 0.80 | HTR2B (0.37) | S100A4HTR2CHTR2BMEN1KMT2A | |
| SCHEMBL15395890 | 0.79 | HTR2C (0.34) | S100A4HTR2CHTR2BHTR2AADRB1 | |
| SCHEMBL2687868 | 0.75 | CYP2A6 (0.40) | CYP11B1CYP11B2HTT | |
| SCHEMBL3989019 | 0.75 | S100A4 (0.41) | S100A4HTR2CHTR2BHTR2AADRB1 | |
| SCHEMBL16385860 | 0.75 | HTR2C (0.58) | HTR2CHTR2BHTR2AADRB1HTR1A | |
| SCHEMBL19514779 | 0.75 | CYP1A2 (0.42) | S100A4HTR2CHTR2BHTR2AADRB1 | |
| SCHEMBL9633548 | 0.75 | AHR (0.54) | HTR2CHTR2BHTR2AADRB1HTR1A | |
| SCHEMBL8993321 | 0.75 | HTR2B (0.40) | S100A4HTR2CHTR2BHTR2AADRB1 | |
| SCHEMBL30633075 | 0.75 | HTR2B (0.40) | S100A4HTR2CHTR2BHTR2AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947592-A | Preparation method of 2, 7-dichlorofluorene derivative | 浙江工业大学 | 2023-10-27 | — | — | CN | disclosed |
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5472973-A | Non-steroidal antiinflammatory agents | SCIOS NOVA INC. (US) | 1995-12-05 | — | — | US | disclosed |
| WO-1993011764-A1 | FLUORENYL DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCIOS NOVA INC. (US) | 1993-06-24 | — | — | WO | disclosed |