Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 10/20 | 0.50 |
| ▸ | HTR2A | P28223 | 9/20 | 0.50 |
| ▸ | HRH1 | P35367 | 5/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD1 | P21728 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633544 | 0.78 | AHR (0.54) | AHRHTR2CHTR2AHRH1ADRA2A | |
| SCHEMBL8993316 | 0.75 | S100A4 (0.41) | AHRHTR2CHTR2AHRH1ADRA2A | |
| SCHEMBL30633032 | 0.75 | S100A4 (0.41) | AHRHTR2CHTR2AHRH1ADRA2A | |
| SCHEMBL6906648 | 0.74 | ALDH1A1 (0.44) | DRD2DRD3DRD4MAPK1 | |
| SCHEMBL16385819 | 0.74 | HTR2A (0.43) | HTR2CHTR2AHRH1ADRA2AADRA2C | |
| SCHEMBL9631975 | 0.74 | AHR (0.48) | AHRHTR2CHTR2AHRH1ADRA2A | |
| SCHEMBL1146208 | 0.74 | DRD2 (0.85) | AHRHTR2CHTR2AHRH1ADRA2A | |
| SCHEMBL3874189 | 0.72 | AHR (0.47) | AHRHTR2CHTR2AHRH1ADRA2A | |
| SCHEMBL1146066 | 0.72 | HTR2C (0.53) | AHRHTR2CHTR2AHRH1ADRA2A | |
| SCHEMBL11343247 | 0.72 | IDO1 (0.44) | HTR2CHTR2AHRH1ADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101059-A | Xanthene compounds | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| WO-1991008190-A1 | AMINO ACID PROTECTING GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-06-13 | — | — | WO | disclosed |