Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851135 | 0.79 | TDP1 (0.59) | ALDH1A1TDP1GAANPC1RAB9A | |
| SCHEMBL31069449 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL11159476 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL789292 | 0.77 | SCN1A (0.47) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL788751 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL789349 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL28112769 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL29152971 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TDP1MEN1KMT2AHPGD | |
| SCHEMBL18550722 | 0.75 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL899473 | 0.75 | ALDH1A1 (0.57) | ALDH1A1TDP1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |