Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.59 |
| ▸ | CCR4 | P51679 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592837 | 0.84 | PLA2G7 (0.50) | TDP1ALDH1A1PLA2G7RAB9ANPC1 | |
| SCHEMBL28188740 | 0.79 | SMN1; SMN2 (0.49) | TDP1ALDH1A1PLA2G7RAB9ANPC1 | |
| SCHEMBL28112317 | 0.79 | PLA2G7 (0.56) | TDP1ALDH1A1PLA2G7RAB9ANPC1 | |
| SCHEMBL899333 | 0.79 | ALDH1A1 (0.59) | TDP1ALDH1A1PLA2G7RAB9ANPC1 | |
| SCHEMBL31069449 | 0.79 | ALDH1A1 (0.59) | TDP1ALDH1A1PLA2G7RAB9ANPC1 | |
| SCHEMBL11159476 | 0.79 | ALDH1A1 (0.59) | TDP1ALDH1A1PLA2G7RAB9ANPC1 | |
| SCHEMBL899473 | 0.78 | ALDH1A1 (0.57) | TDP1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18550722 | 0.78 | ALDH1A1 (0.59) | TDP1ALDH1A1PLA2G7RAB9ANPC1 | |
| SCHEMBL31213422 | 0.77 | NPC1 (0.55) | TDP1ALDH1A1PLA2G7RAB9ANPC1 | |
| SCHEMBL5850472 | 0.77 | ALDH1A1 (0.50) | TDP1ALDH1A1PLA2G7CCR4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699749-A | Application of 5-piperonyl thiazole derivative as anticancer drug | 湖南大学 | 2017-05-24 | — | — | CN | disclosed |
| EP-0421464-A1 | Method for storing infrared-sensitive silver halide photographic material and photographic composite composed of infrared-sensitive silver halide photographic material and packaging material thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0138543-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |