Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 12/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 12/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 12/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899333 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL789349 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL789292 | 0.72 | SCN1A (0.47) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL11159476 | 0.70 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL9851135 | 0.70 | TDP1 (0.59) | ALDH1A1TDP1GAALMNASMN1; SMN2 | |
| SCHEMBL31069449 | 0.70 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL31566949 | 0.69 | SCN1A (0.61) | ALDH1A1TDP1SCN1ASCN5ASCN8A | |
| SCHEMBL27700307 | 0.69 | EGFR (0.56) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL5850472 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL3529264 | 0.69 | ALDH1A1 (0.47) | ALDH1A1TDP1MEN1KMT2ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |