SCHEMBL8993364

SCHEMBL8993364

COc1ccc(Cc2ccc(CO)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.65
SAE1 Q9UBE0 1/20 0.56
UBA2 Q9UBT2 1/20 0.56
IDO1 P14902 3/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CALM1 P0DP23 1/20 0.48
AGXT P21549 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
ALDH1A1 P00352 3/20 0.47
CYP2D6 P10635 1/20 0.47
ATM Q13315 1/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HTT P42858 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4181089 0.93 IDO1 (0.58) LTA4HIDO1CA12CA1CA2
SCHEMBL27329 0.93 IDO1 (0.58) LTA4HIDO1CA12CA1CA2
Methyl Alcohol SCHEMBL28311094 0.91 IDO1 (0.56) LTA4HIDO1CA12CA1CA2
Methoxymethane SCHEMBL28284584 0.91 IDO1 (0.56) LTA4HIDO1CA12CA1CA2
SCHEMBL1475480 0.91 IDO1 (0.56) LTA4HIDO1CA12CA1CA2
SCHEMBL1477048 0.91 IDO1 (0.56) LTA4HIDO1CA12CA1CA2
SCHEMBL9892953 0.89 LTA4H (0.53) LTA4HSAE1UBA2IDO1CALM1
Alcohol SCHEMBL2947640 0.88 IDO1 (0.54) LTA4HIDO1CA12CA1CA2
SCHEMBL27884 0.88 LTA4H (0.81) LTA4HSAE1UBA2IDO1CA12
SCHEMBL25986524 0.88 LTA4H (0.81) LTA4HSAE1UBA2IDO1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108504641-A Alcohol dehydrogenase mutant and its application in the synthesis of double aryl chiral alcohols 江南大学 2018-09-07 CN disclosed
US-9738606-B2 Substituted diarylamines and use of same as antioxidants QUEEN'S UNIVERSITY AT KINGSTON (CA) 2017-08-22 US disclosed
US-9562124-B2 Thermo-oxidatively stable, side chain polyether functionalized polynorbornenes for microelectronic and optoelectronic devices and assemblies thereof PROMERUS, LLC (US) 2017-02-07 US disclosed
US-20160319060-A1 Thermo-oxidatively Stable, Side Chain Polyether Functionalized Polynorbornenes for Microelectronic and Optoelectronic Devices and Assemblies Thereof PROMERUS, LLC (US) 2016-11-03 US disclosed
US-9425404-B2 Thermo-oxidatively stable, side chain polyether functionalized polynorbornenes for microelectronic and optoelectronic devices and assemblies thereof PROMERUS, LLC (US) 2016-08-23 US disclosed
US-20150275076-A1 Non-crystallizable Pi-conjugated Molecular Glass Mixtures, Charge Transporting Molecular Glass Mixtures, Luminescent Molecular Glass Mixtures, or Combinations Thereof for Organic Light Emitting Diodes and other Organic Electronics and Photonics Applications Molaire Consulting 2015-10-01 US disclosed
US-20140206585-A1 Substituted Diarylamines and Use of Same as Antioxidants UNIVERSITA DI BOLOGNA (IT) 2014-07-24 US disclosed
US-20130181199-A1 Thermo-oxidatively Stable, Side Chain Polyether Functionalized Polynorbornenes for Microelectronic and Optoelectronic Devices and Assemblies Thereof SUMITOMO BAKELITE CO., LTD. (JP) 2013-07-18 US disclosed
EP-2381308-A2 Positive-working photosensitive resin composition, method for producing pattern-formed resin film, semiconductor device, display device, and method for producing the semiconductor device and the display device SUMITOMO BAKELITE CO., LTD. (JP) 2011-10-26 EP disclosed
US-7741007-B2 Lithography; semiconductor microfabrication SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20080220369-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-11 US disclosed
US-20080213695-A1 Lithography; semiconductor microfabrication SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-7361445-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY (JP) 2008-04-22 US disclosed
US-5516777-A PROSTATE CANCER THERAPY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-05-14 US disclosed
US-5409928-A Prostate diseases, alopecia OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-04-25 US disclosed
EP-0594149-A2 Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-04-27 EP disclosed
US-4208425-A VIRICIDES STERLING DRUG INC. (US) 1980-06-17 US disclosed
US-4171371-A Diketones STERLING DRUG INC. (US) 1979-10-16 US disclosed
US-4153719-A Aromatic diketones STERLING DRUG INC. (US) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140206585-A1 Substituted Diarylamines and Use of Same as Antioxidants SOD1, NQO1, GPX1 LTA4H 2705/4885SAE1 2923/4885UBA2 1443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.