Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884019 | 0.95 | LTA4H (0.49) | LTA4HSAE1UBA2IDO1AOC3 | |
| SCHEMBL11890477 | 0.95 | LTA4H (0.49) | LTA4HSAE1UBA2AOC3CALM1 | |
| SCHEMBL3929503 | 0.94 | IDO1 (0.47) | LTA4HIDO1AOC3ALDH1A1CYP3A4 | |
| SCHEMBL12732320 | 0.94 | IDO1 (0.47) | LTA4HIDO1AOC3ALDH1A1CYP3A4 | |
| SCHEMBL10062238 | 0.94 | IDO1 (0.47) | LTA4HIDO1AOC3ALDH1A1CYP3A4 | |
| SCHEMBL806274 | 0.94 | LTA4H (0.47) | LTA4HSAE1UBA2ALDH1A1MAPK1 | |
| SCHEMBL22382224 | 0.91 | LTA4H (0.63) | LTA4HSAE1UBA2IDO1AOC3 | |
| SCHEMBL12611356 | 0.89 | MAOB (0.49) | IDO1AOC3MAPK1CALM1NR1I2 | |
| SCHEMBL14769812 | 0.89 | LMNA (0.46) | LTA4HIDO1AOC3ALDH1A1CALM1 | |
| SCHEMBL12200966 | 0.89 | MAOB (0.49) | IDO1AOC3MAPK1CALM1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142948-A1 | TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND | RICOH COMPANY, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142948-A1 | TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND | CYP4A11, CYP11B1, CYP11B2 | LTA4H 2147/4885SAE1 2200/4885UBA2 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.