Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652669 | 0.86 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL8655910 | 0.85 | PTGS2 (0.59) | PTGS2PTGS1CA1CA2 | |
| SCHEMBL8653038 | 0.78 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL8993369 | 0.77 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL8387384 | 0.76 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL8993420 | 0.75 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL7865484 | 0.75 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL8993402 | 0.73 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL8656040 | 0.73 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL8654191 | 0.73 | PTGS2 (0.68) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | disclosed |