Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.54 |
| ▸ | KDM5A | P29375 | 2/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567987 | 0.90 | ALDH1A1 (0.49) | KDM4CKDM5AKDM5BKDM4EPARP1 | |
| SCHEMBL5623941 | 0.78 | HTR6 (0.51) | KDM4CKDM5AKDM5BPARP1PARP2 | |
| SCHEMBL9567996 | 0.78 | ALDH1A1 (0.51) | KDM4CKDM5AKDM5BKDM4EKMT2A | |
| SCHEMBL9568077 | 0.76 | TRPV1 (0.46) | KDM4CKDM5AKDM5BL3MBTL1ALDH1A1 | |
| SCHEMBL9567963 | 0.76 | ALDH1A1 (0.44) | KDM4CKDM5AKDM5BKMT2AL3MBTL1 | |
| SCHEMBL1566782 | 0.76 | SIGMAR1 (0.49) | PARP1PARP2ALDH1A1 | |
| SCHEMBL9568002 | 0.74 | MEN1 (0.49) | KDM4CKDM5AKDM5BKMT2AMEN1 | |
| SCHEMBL10585088 | 0.74 | CYP19A1 (0.48) | KDM4CKDM5AKDM5BPARP1PARP2 | |
| SCHEMBL8993427 | 0.74 | HCAR2 (0.52) | KDM4EKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL9568047 | 0.74 | TRPV1 (0.44) | KDM4CKDM5AKDM5BPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191378-A1 | Anthranilic acid derivatives and their use as activators of the hm74a receptor | SMITHKLINE BEECHAM CORPORATION (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191378-A1 | Anthranilic acid derivatives and their use as activators of the hm74a receptor | SMITHKLINE BEECHAM CORPORATION (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191378-A1 | Anthranilic acid derivatives and their use as activators of the hm74a receptor | SMITHKLINE BEECHAM CORPORATION (US) | 2007-08-16 | — | — | US | disclosed |
| EP-1689699-A2 | ANTHRANILIC ACID DERIVATIVES AND THEIR USE AS ACTIVATORS OF THE HM74A RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005016867-A2 | ANTHRANILIC ACID DERIVATIVES AND THEIR USE AS ACTIVATORS OF THE HM74A RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191378-A1 | Anthranilic acid derivatives and their use as activators of the hm74a receptor | ANTXR2, HCAR1, GPR88 | KDM4C 4812/4885KDM5A 4454/4885KDM5B 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.