SCHEMBL8993438

SCHEMBL8993438

CCNS(=O)(=O)c1ccccc1C=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.44
CA9 Q16790 5/20 0.44
ALDH1A1 P00352 5/20 0.42
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX5AP P20292 2/20 0.41
FEN1 P39748 2/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 2/20 0.40
HTT P42858 1/20 0.40
GLA P06280 1/20 0.40
RECQL P46063 1/20 0.40
TSHR P16473 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2801003 0.81 ALDH1A1 (0.44) ALDH1A1LMNAMEN1THRBBLM
SCHEMBL10900779 0.81 RECQL (0.65) CA12CA9ALDH1A1LMNAMEN1
SCHEMBL2662843 0.80 ALDH1A1 (0.46) CA12CA9ALDH1A1LMNAMEN1
SCHEMBL3630587 0.80 CYP2C19 (0.44) CA12CA9ALDH1A1LMNAMEN1
SCHEMBL2798389 0.79 LMNA (0.46) ALDH1A1LMNAMEN1THRBBLM
SCHEMBL2799637 0.79 CA12 (0.58) CA12CA9ALDH1A1LMNAKMT2A
Diethylamine SCHEMBL28827470 0.77 LMNA (0.49) CA12CA9ALDH1A1LMNAMEN1
SCHEMBL16495208 0.77 LMNA (0.48) ALDH1A1LMNAMEN1THRBBLM
SCHEMBL396299 0.77 CA12 (0.47) CA12CA9ALDH1A1LMNAKMT2A
SCHEMBL13232751 0.77 ALDH1A1 (0.38) CA12CA9ALDH1A1LMNAALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543433-A BROAD SPECTRUM; IN PARTICULAR ASCOMYCETES AND BASIDIOMYCETES BASF AKTIENGESELLSCHAFT (DE) 1996-08-06 US disclosed