Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858859 | 0.87 | SMN1; SMN2 (0.59) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL15916488 | 0.81 | LMNA (0.55) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7303768 | 0.81 | SMN1; SMN2 (0.48) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL22724729 | 0.78 | PAX8 (0.51) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL17623909 | 0.76 | MEN1 (0.56) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL1748539 | 0.75 | SMN1; SMN2 (0.55) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL10411730 | 0.75 | PAX8 (0.56) | MEN1KMT2AHPGDSMN1; SMN2TSHR | |
| SCHEMBL127000 | 0.75 | TSHR (0.65) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL29637724 | 0.75 | TSHR (0.65) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL19317602 | 0.74 | KMT2A (0.50) | MEN1KMT2AHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315889-B1 | Pyrimidine derivatives, processes for their production, and herbicidal method and compositions | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1996-07-17 | — | — | EP | disclosed |
| EP-0335409-B1 | Pyrimidine derivatives, processes for their production and herbicidal compositions containing them | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4969949-A | NONPHYTOTOXIC | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-13 | — | — | US | disclosed |
| US-4923501-A | COTTON; NONPHYTOTOXIC | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0335409-A2 | Pyrimidine derivatives, processes for their production and herbicidal compositions containing them | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |
| EP-0315889-A2 | Pyrimidine derivatives, processes for their production, and herbicidal method and compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-05-17 | — | — | EP | disclosed |