SCHEMBL8993447

SCHEMBL8993447

Cc1cccc(Oc2nc(C)cc(C)n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
HTT P42858 4/20 0.50
ACHE P22303 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GAA P10253 2/20 0.47
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PTGS1 P23219 1/20 0.45
LYN P07948 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.43
MAP4K4 O95819 1/20 0.42
GCK P35557 1/20 0.42
THRB P10828 1/20 0.41
TSHR P16473 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9190084 0.90 HTT (0.51) ALDH1A1HTTMEN1KMT2AGAA
SCHEMBL10411730 0.82 PAX8 (0.56) ALDH1A1HTTMEN1KMT2AGAA
SCHEMBL29673035 0.81 HTT (0.55) ALDH1A1HTTACHEMEN1KMT2A
SCHEMBL14189347 0.80 L3MBTL1 (0.61) ALDH1A1HTTACHEMEN1KMT2A
SCHEMBL456868 0.79 ALDH1A1 (0.72) ALDH1A1HTTACHEMEN1KMT2A
SCHEMBL29398372 0.79 ALDH1A1 (0.72) ALDH1A1HTTACHEMEN1KMT2A
SCHEMBL29746015 0.79 ALDH1A1 (0.72) ALDH1A1HTTACHEMEN1KMT2A
SCHEMBL12409092 0.78 MEN1 (0.59) ALDH1A1HTTACHEMEN1KMT2A
SCHEMBL9379271 0.78 HTT (0.61) ALDH1A1HTTACHEMEN1KMT2A
SCHEMBL22404417 0.78 ALDH1A1 (0.47) ALDH1A1HTTACHEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315889-B1 Pyrimidine derivatives, processes for their production, and herbicidal method and compositions KUMIAI CHEMICAL INDUSTRY CO (JP) 1996-07-17 EP disclosed
US-4923501-A COTTON; NONPHYTOTOXIC KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-05-08 US disclosed
EP-0315889-A2 Pyrimidine derivatives, processes for their production, and herbicidal method and compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-05-17 EP disclosed