Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477199 | 0.83 | ALOX15 (0.43) | ALDH1A1L3MBTL1KMT2ARAB9AMEN1 | |
| SCHEMBL38657760 | 0.83 | ALOX15 (0.43) | ALDH1A1LMNAL3MBTL1KMT2ARAB9A | |
| SCHEMBL2511600 | 0.83 | CDK9 (0.52) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL15897676 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AHTTMEN1 | |
| SCHEMBL2511601 | 0.83 | CDK9 (0.52) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL2508847 | 0.83 | ATM (0.47) | ALDH1A1L3MBTL1KMT2APKMRAB9A | |
| SCHEMBL2508849 | 0.83 | ATM (0.47) | ALDH1A1L3MBTL1KMT2APKMRAB9A | |
| SCHEMBL28559709 | 0.81 | MAPT (0.57) | ALDH1A1LMNAKMT2AHTTPKM | |
| SCHEMBL20588753 | 0.81 | CDK9 (0.41) | ALDH1A1L3MBTL1KMT2AHTTRAB9A | |
| SCHEMBL14755669 | 0.81 | PARP10 (0.44) | HTTALOX15TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | disclosed |