Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993584 | 0.90 | MEN1 (0.37) | GABRA1GABRG2GABRB3GABRA5CRHR1 | |
| SCHEMBL8993529 | 0.82 | TDP1 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6699195 | 0.78 | CYP4F2 (0.44) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6908332 | 0.77 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9520570 | 0.76 | GAA (0.37) | GABRA1GABRG2GABRB3GABRA5HTR4 | |
| SCHEMBL6697536 | 0.74 | MEN1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7953670 | 0.74 | KMT2A (0.37) | CRHR1MEN1KMT2AALDH1A1RORC | |
| SCHEMBL9567016 | 0.73 | CTSB (0.36) | CRHR1MEN1KMT2A | |
| SCHEMBL4897613 | 0.72 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL44446 | 0.72 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527764-A | 3-arylthionouracils useful as herbicides, defoliants, and desiccants | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-06-18 | — | — | US | disclosed |