Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729826 | 1.00 | CRHBP (0.61) | CRHBPCRHR2HSD11B1AKR1C1LMNA | |
| SCHEMBL19877927 | 0.83 | CRHBP (0.44) | CRHBPCRHR2AKR1C1LMNAHTT | |
| SCHEMBL570250 | 0.79 | HTT (0.50) | CRHBPCRHR2LMNAHTTPOLB | |
| SCHEMBL14968010 | 0.77 | ALDH1A1 (0.42) | CRHBPCRHR2HTTPOLBALDH1A1 | |
| SCHEMBL18316474 | 0.75 | CRHBP (0.44) | CRHBPCRHR2HSD11B1AKR1C1HTT | |
| SCHEMBL31354802 | 0.75 | CRHBP (0.44) | CRHBPCRHR2HSD11B1AKR1C1HTT | |
| SCHEMBL2234611 | 0.75 | CRHBP (0.44) | CRHBPCRHR2HSD11B1AKR1C1HTT | |
| SCHEMBL14967867 | 0.75 | CRHBP (0.38) | CRHBPCRHR2HTTALDH1A1 | |
| SCHEMBL14968071 | 0.75 | TSHR (0.40) | CRHBPCRHR2LMNAHTTALDH1A1 | |
| SCHEMBL14968000 | 0.75 | TSHR (0.50) | HTTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |