Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26782114 | 0.98 | CHRM2 (0.46) | MAOAADRA2CCHRM2CARM1PRMT6 | |
| Iodide SCHEMBL10492775 | 0.98 | ADRA2C (0.42) | MAOAADRA2CCHRM2CARM1PRMT6 | |
| SCHEMBL544087 | 0.94 | ADRA2C (0.49) | ADRA2CCARM1PRMT6PRMT8AOC3 | |
| SCHEMBL13645984 | 0.89 | SIGMAR1 (0.48) | AOC3SIGMAR1CA12CA2CA9 | |
| SCHEMBL8643584 | 0.88 | CHRM2 (0.46) | CHRM2SIGMAR1CA12CA2CA9 | |
| SCHEMBL17037834 | 0.87 | SIGMAR1 (0.52) | AOC3SIGMAR1CA12CA2CA9 | |
| Hydrochloric Acid SCHEMBL8647546 | 0.87 | CHRM2 (0.44) | CHRM2 | |
| SCHEMBL4395973 | 0.85 | CARM1 (0.52) | ADRA2CCARM1PRMT6PRMT8AOC3 | |
| SCHEMBL11145951 | 0.84 | CA12 (0.47) | AOC3SIGMAR1CA12CA2CA9 | |
| Hydrochloric Acid SCHEMBL6890412 | 0.83 | CARM1 (0.50) | ADRA2CCARM1PRMT6PRMT8AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532171-A | PHENOTHIAZINE DYES FOR PHOTODYNAMIC THERAPY OF CANCER OR IMMUNOASSAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5344928-A | Phenothiazine compounds for cancer treatment or immunoassay using chemiluminescence | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0510668-A2 | Phenothiazine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |