Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL576999 | 0.73 | LMNA (0.47) | TOP2AMAOAMAOBNPSR1LMNA | |
| SCHEMBL3530370 | 0.71 | TOP2A (0.42) | TOP2AMAOAMAOBNPSR1LMNA | |
| SCHEMBL11696413 | 0.70 | CNR2 (0.43) | TOP2AMAOAMAOBNPSR1LMNA | |
| SCHEMBL6380088 | 0.67 | MAOA (0.42) | MAOAMAOBNPSR1LMNAHTT | |
| SCHEMBL576279 | 0.67 | L3MBTL1 (0.45) | MAOAMAOBNPSR1LMNAHTT | |
| Hydrochloric Acid SCHEMBL28211399 | 0.66 | L3MBTL1 (0.44) | MAOAMAOBNPSR1LMNAHTT | |
| SCHEMBL8315407 | 0.66 | MAOA (0.37) | TOP2AMAOAMAOBNPSR1LMNA | |
| SCHEMBL11498993 | 0.65 | MAOA (0.43) | MAOAMAOBLMNAALDH1A1TSHR | |
| SCHEMBL10442397 | 0.64 | MAOA (0.48) | MAOAMAOBNPSR1LMNAHTT | |
| SCHEMBL7353378 | 0.64 | ELANE (0.40) | MAOAMAOBNPSR1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484925-A | Synthesis of (-)-swainsonine and intermediate compounds employed in such synthesis | GLYCODESIGN HOLDINGS LTD. (CA) | 1996-01-16 | — | — | US | disclosed |
| US-5288875-A | Synthesis of (-)-swainsonine and intermediate compounds employed in such synthesis | GLYCODESIGN HOLDINGS LTD. (CA) | 1994-02-22 | — | — | US | disclosed |
| US-5187279-A | Synthesis of (-) swainsonine and intermediate compounds employed in such synthesis | GLYCODESIGN HOLDINGS LTD. (CA) | 1993-02-16 | — | — | US | disclosed |
| WO-1990006311-A1 | SYNTHESIS OF (-)-SWAINSONINE AND INTERMEDIATE COMPOUNDS EMPLOYED IN SUCH SYNTHESIS | VANDERBILT UNIVERSITY (US) | 1990-06-14 | — | — | WO | disclosed |