SCHEMBL2510044

SCHEMBL2510044

O=P(O)(O)O[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1OP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ITPR3 Q14573 8/20 1.00
ITPR2 Q14571 4/20 1.00
ITPR1 Q14643 4/20 1.00
INPP5A Q14642 2/20 0.84
INPPL1 O15357 1/20 0.75
AKT1 P31749 1/20 0.75
SMPD1 P17405 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9091859 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9093199 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9094714 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL8994052 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9091912 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL405897 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL8775574 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL2044892 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9387601 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL15067019 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240181062-A1 RED-SHIFTED PHOTOLIPIDS AND NANOPARTICLES FORMED FROM SAME THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-06-06 US claimed
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 US disclosed
US-20240181062-A1 RED-SHIFTED PHOTOLIPIDS AND NANOPARTICLES FORMED FROM SAME THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-06-06 US disclosed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
EP-3131543-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF LIPID STORAGE DISORDERS Neurotrope Bioscience (US) 2017-02-22 EP disclosed
WO-2015160851-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF LIPID STORAGE DISORDERS NEUROTROPE BIOSCIENCE (US) 2015-10-22 WO disclosed
US-20140309186-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION 2014-10-16 US disclosed
US-20110246081-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-06 US disclosed
WO-2009052186-A1 METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS GEORGIA TECH RESEARCH CORPORATION (US) 2009-04-23 WO disclosed
US-20050148042-A1 Hybrid phosphoinositide phospholipids: compositions and uses NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-07-07 US disclosed
US-6384260-B1 ANALOGUES OF PHOSPHATIDYLINOSITOL-PHOSPHATES SUCH AS 1D-3,6-DI-O-BENZYL-MYO-INOSITOL AS RESEARCH REAGENTS, STRUCTURE- AND MECHANISM-BASED COMPETITIVE INHIBITORS; REPORTER OR ANCHORING GROUPS; CHEMICAL INTERMEDIATES NUTRIMED BIOTECH 2002-05-07 US disclosed
US-6232486-B1 PHOSPHATIDYLINOSITOL PHOSPHATE NUTRIMED BIOTECH 2001-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR ITPR3 4386/4885ITPR2 4181/4885ITPR1 4140/4885
US-20240181062-A1 RED-SHIFTED PHOTOLIPIDS AND NANOPARTICLES FORMED FROM SAME PLTP, SGMS2, PHOSPHO1 ITPR3 1153/4885ITPR2 807/4885ITPR1 836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.