SCHEMBL8994400

SCHEMBL8994400

N#Cc1c(Cl)c(C(F)(F)F)n(CC2(C(=O)O)CCC2)c1-c1ccc(Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
HPGD P15428 2/20 0.33
GRIA2 P42262 1/20 0.33
GRIA4 P48058 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
CRHBP P24387 1/20 0.33
HTT P42858 1/20 0.33
CRHR2 Q13324 1/20 0.33
CNR1 P21554 2/20 0.32
RXFP1 Q9HBX9 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PIK3CA P42336 1/20 0.31
PSEN1 P49768 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994385 0.96 POLB (0.37) POLBMAPTALDH1A1KDM4EMEN1
SCHEMBL8994380 0.87 POLB (0.34) POLBMAPTALDH1A1KDM4EMEN1
SCHEMBL8994487 0.86 POLB (0.36) POLBMAPTALDH1A1KDM4EMEN1
SCHEMBL8994415 0.81 ALOX5AP (0.33) MEN1KMT2AGRIA2GRIA4PSEN1
SCHEMBL8994389 0.79 ADORA1 (0.34) POLBMAPTGRIA2GRIA4RXFP1
SCHEMBL7494704 0.76 KDM4E (0.39) POLBMAPTALDH1A1KDM4EMEN1
SCHEMBL9460809 0.75 POLB (0.39) POLBMAPTALDH1A1KDM4EMEN1
SCHEMBL9036743 0.75 KDM4E (0.38) POLBMAPTALDH1A1KDM4EMEN1
SCHEMBL9036502 0.74 PPARG (0.33) POLBMAPTGRIA2GRIA4PIK3CA
SCHEMBL9460811 0.74 POLB (0.37) POLBMAPTALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594941-B1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed