Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460811 | 0.85 | POLB (0.37) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7494704 | 0.80 | KDM4E (0.39) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL9036743 | 0.79 | KDM4E (0.38) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL8994385 | 0.77 | POLB (0.37) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL5815133 | 0.76 | KDM4E (0.36) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL8994400 | 0.75 | POLB (0.36) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL8994390 | 0.75 | L3MBTL1 (0.35) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL9017388 | 0.75 | POLB (0.37) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL5812558 | 0.74 | RXFP1 (0.36) | POLBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL9460941 | 0.74 | POLB (0.36) | POLBMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254559-A | Insecticidal, acaricidal and molluscicidal 1-(substituted)thioalkylpyrroles | AMERICAN CYANAMID COMPANY (US) | 1993-10-19 | — | — | US | claimed |