Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994380 | 0.95 | POLB (0.34) | POLBMAPTGRIA2GRIA4ALDH1A1 | |
| SCHEMBL8994385 | 0.90 | POLB (0.37) | POLBMAPTGRIA2GRIA4ALDH1A1 | |
| SCHEMBL8994400 | 0.86 | POLB (0.36) | POLBMAPTGRIA2GRIA4ALDH1A1 | |
| SCHEMBL9036502 | 0.84 | PPARG (0.33) | POLBMAPTGRIA2GRIA4PIK3CA | |
| SCHEMBL8994468 | 0.79 | RXFP1 (0.35) | POLBMAPTGRIA2GRIA4ALDH1A1 | |
| SCHEMBL7508068 | 0.79 | KDM4E (0.37) | POLBMAPTGRIA2GRIA4ALDH1A1 | |
| SCHEMBL7499361 | 0.79 | KDM4E (0.37) | POLBMAPTGRIA2GRIA4ALDH1A1 | |
| SCHEMBL9057679 | 0.78 | HTT (0.36) | POLBMAPTGRIA2GRIA4ALDH1A1 | |
| SCHEMBL8994408 | 0.78 | OPRM1 (0.38) | LMNAHTT | |
| SCHEMBL7504784 | 0.77 | MAPT (0.35) | POLBMAPTGRIA2GRIA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594941-B1 | N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents | AMERICAN CYANAMID CO (US) | 1996-08-14 | — | — | EP | claimed |