SCHEMBL8994415

SCHEMBL8994415

N#Cc1c(Cl)c(Cl)n(CC2(C(=O)O)CCCCC2)c1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.33
ADORA1 P30542 1/20 0.33
DPP4 P27487 1/20 0.32
FAP Q12884 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
APP P05067 2/20 0.32
RXRA P19793 1/20 0.32
RXRG P48443 1/20 0.32
CACNA1G O43497 1/20 0.32
KCNH2 Q12809 1/20 0.32
ARG1 P05089 1/20 0.31
KIF11 P52732 1/20 0.31
GRIA2 P42262 1/20 0.31
GRIA4 P48058 1/20 0.31
EPHX2 P34913 1/20 0.31
P2RX7 Q99572 1/20 0.31
DRD2 P14416 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994389 0.95 ADORA1 (0.34) ADORA1DPP4FAPDPP8DPP9
SCHEMBL8994400 0.81 POLB (0.36) GRIA2GRIA4MEN1KMT2APSEN1
SCHEMBL8994380 0.78 POLB (0.34) GRIA2GRIA4MEN1KMT2A
SCHEMBL8994385 0.78 POLB (0.37) GRIA2GRIA4MEN1KMT2APSEN1
SCHEMBL9058461 0.77 ADORA1 (0.43) ADORA1KIF11GRIA2GRIA4RET
SCHEMBL9057391 0.76 GRIA2 (0.38) ADORA1APPRXRARXRGKIF11
SCHEMBL8994414 0.74 MGLL (0.36) APPPSEN1PSEN2APH1BNCSTN
SCHEMBL9059293 0.74 KIF11 (0.41) ADORA1KIF11RETMEN1CYP3A4
SCHEMBL9222722 0.74 ADORA1 (0.35) ADORA1KIF11GRIA2GRIA4RET
SCHEMBL8994418 0.73 POLB (0.34) APPGRIA2GRIA4MCHR1PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594941-B1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed