Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22710272 | 0.94 | TDP1 (0.59) | TDP1MAPK14MEN1KMT2ALMNA | |
| SCHEMBL10387224 | 0.87 | MAPK14 (0.50) | MAPK14MEN1KMT2ALTA4HMAPT | |
| SCHEMBL9833964 | 0.87 | MAPK14 (0.50) | MAPK14MEN1KMT2ALTA4HMAPT | |
| SCHEMBL9833970 | 0.87 | MAPK14 (0.50) | MAPK14MEN1KMT2ALTA4HMAPT | |
| SCHEMBL10417445 | 0.86 | TDP1 (0.46) | TDP1MAPK14MEN1KMT2ALMNA | |
| SCHEMBL7595684 | 0.86 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL8724412 | 0.85 | APP (0.46) | TDP1MAPK14MEN1KMT2ALMNA | |
| SCHEMBL7594473 | 0.84 | MAPK14 (0.48) | MAPK14CA2 | |
| SCHEMBL6267008 | 0.84 | PKM (0.51) | TDP1MAPK14MEN1KMT2ALMNA | |
| SCHEMBL898113 | 0.84 | CA2 (0.45) | TDP1MAPK14MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501912-B1 | Methyldioxolane | CIBA GEIGY AG (CH) | 1996-08-14 | — | — | EP | disclosed |
| US-5478958-A | Stereoselective acetalization catalyst | CIBA-GEIGY CORPORATION (US) | 1995-12-26 | — | — | US | disclosed |
| US-5384416-A | Stereospecific insecticides | CIBA-GEIGY CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
| US-5280041-A | Such as 4-((4-phenoxyphenoxy)methyl)dioxolan | CIBA-GEIGY CORPORATION (US) | 1994-01-18 | — | — | US | disclosed |
| EP-0501912-A1 | Methyldioxolane | CIBA-GEIGY AG (CH) | 1992-09-02 | — | — | EP | disclosed |