Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387224 | 1.00 | MAPK14 (0.50) | MAPK14FPR2SCN9ALTA4HCA2 | |
| SCHEMBL9833964 | 1.00 | MAPK14 (0.50) | MAPK14FPR2SCN9ALTA4HCA2 | |
| SCHEMBL9774729 | 0.96 | MAPK14 (0.53) | MAPK14CA2APPDRD4MEN1 | |
| SCHEMBL9774733 | 0.96 | MAPK14 (0.53) | MAPK14CA2APPDRD4MEN1 | |
| SCHEMBL7594473 | 0.91 | MAPK14 (0.48) | MAPK14FPR2SCN9ACA2 | |
| SCHEMBL7595684 | 0.87 | MAPK14 (0.48) | MAPK14DRD4TP53TSHR | |
| SCHEMBL8994562 | 0.87 | TDP1 (0.53) | MAPK14LTA4HCA2MEN1MAPT | |
| SCHEMBL6267008 | 0.82 | PKM (0.51) | MAPK14CA2APPDRD4MEN1 | |
| SCHEMBL898113 | 0.82 | CA2 (0.45) | MAPK14CA2APPMEN1TP53 | |
| SCHEMBL898114 | 0.82 | CA2 (0.45) | MAPK14CA2APPMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276196-B1 | SUBSTITUTED DIOXOLANE DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-09-18 | — | — | EP | disclosed |
| US-4971981-A | PESTICIDES, INSECTICIDES, LARVICIDES | CIBA-GEIGY CORPORATION (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0276196-A1 | Substituted dioxolane derivatives | CIBA-GEIGY AG (CH) | 1988-07-27 | — | — | EP | disclosed |