Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435998 | 0.95 | ITGB3 (0.46) | PTPN1FAAHITGB3ITGA2BEPHX2 | |
| SCHEMBL12071641 | 0.87 | ALOX15 (0.42) | FAAHITGB3ITGA2BEPHX2MEN1 | |
| SCHEMBL8770853 | 0.87 | ITGB3 (0.50) | FAAHITGB3ITGA2BEPHX2MEN1 | |
| SCHEMBL8770877 | 0.86 | PRMT1 (0.55) | ITGB3ITGA2BEPHX2MEN1KMT2A | |
| SCHEMBL26870168 | 0.86 | PRMT1 (0.55) | ITGB3ITGA2BEPHX2MEN1KMT2A | |
| SCHEMBL24620412 | 0.86 | SMN1; SMN2 (0.44) | FAAHITGB3ITGA2BEPHX2MEN1 | |
| SCHEMBL3986924 | 0.86 | PRMT1 (0.55) | ITGB3ITGA2BEPHX2MEN1KMT2A | |
| SCHEMBL9352934 | 0.85 | PTPN1 (0.47) | PTPN1FAAHITGB3ITGA2BEPHX2 | |
| SCHEMBL9352921 | 0.85 | PTPN1 (0.47) | PTPN1FAAHITGB3ITGA2BEPHX2 | |
| SCHEMBL13121767 | 0.84 | ALOX15 (0.40) | FAAHITGB3ITGA2BEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540574-B1 | ANTICOAGULANT PEPTIDES | MERRELL PHARMA INC (US) | 1996-09-11 | — | — | EP | claimed |
| EP-0540574-A4 | — | — | 1994-04-27 | — | — | EP | claimed |
| EP-0540574-A1 | ANTICOAGULANT PEPTIDES. | MERRELL DOW PHARMA (US) | 1993-05-12 | — | — | EP | claimed |
| WO-1992001710-A1 | ANTICOAGULANT PEPTIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-02-06 | — | — | WO | claimed |
| EP-0540574-B1 | ANTICOAGULANT PEPTIDES | MERRELL PHARMA INC (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5495000-A | Anticoagulant peptides | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-27 | — | — | US | disclosed |
| EP-0540574-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0540574-A1 | ANTICOAGULANT PEPTIDES. | MERRELL DOW PHARMA (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001710-A1 | ANTICOAGULANT PEPTIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-02-06 | — | — | WO | disclosed |