SCHEMBL8994836

SCHEMBL8994836

O=C1C=C([Na])c2ccccc2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 9/20 0.56
PTPRC P08575 6/20 0.56
MAPT P10636 3/20 0.56
KDM4E B2RXH2 2/20 0.56
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 1/20 0.56
CYP3A4 P08684 1/20 0.56
HPGD P15428 1/20 0.56
PTPN22 Q9Y2R2 1/20 0.56
NSD2 O96028 1/20 0.56
HKDC1 Q2TB90 1/20 0.56
CDC25B P30305 3/20 0.52
PTPRF P10586 2/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MALT1 Q9UDY8 2/20 0.50
DNMT1 P26358 1/20 0.48
CES2 O00748 2/20 0.48
APAF1 O14727 2/20 0.48
NPC1 O15118 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8600693 0.75 PTPN1 (0.75) PTPN1PTPRCMAPTKDM4EMAPK1
SCHEMBL6052798 0.73 PTPN1 (0.58) PTPN1PTPRCMAPTKDM4EMAPK1
SCHEMBL2529860 0.71 PTPRC (0.59) PTPN1PTPRCMAPTKDM4EMAPK1
SCHEMBL342409 0.71 KDM4E (1.00) PTPN1PTPRCMAPTKDM4EMAPK1
SCHEMBL4647848 0.71 CDC25B (0.68) PTPN1PTPRCMAPTKDM4EMAPK1
4-Amino-[1,2]Naphthoquinone SCHEMBL422308 0.71 PTPN1 (1.00) PTPN1PTPRCMAPTKDM4EMAPK1
SCHEMBL6234343 0.71 PTPRC (1.00) PTPN1PTPRCMAPTKDM4EMAPK1
SCHEMBL30412470 0.71 PTPRC (1.00) PTPN1PTPRCMAPTKDM4EMAPK1
4-Amino-[1,2]Naphthoquinone SCHEMBL5051876 0.70 PTPN1 (0.95) PTPN1PTPRCMAPTKDM4EMAPK1
4-Amino-[1,2]Naphthoquinone SCHEMBL5161711 0.70 PTPN1 (0.95) PTPN1PTPRCMAPTKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115504866-A Preparation method and application of 4-methoxy-2-naphthol 阜阳欣奕华制药科技有限公司 2022-12-23 CN claimed
CN-113697945-B Biomembrane reactor for deep purification of sewage and operation method thereof 南京大学 2022-11-11 CN claimed
US-5489316-A Process for making industrial organic solvents and hydrocarbons used as fuels ENICHEM SYNTHESIS S.P.A. (IT) 1996-02-06 US claimed
EP-0677568-A1 Process for marking industrial organic solvents and hydrocarbons used as fuels ENICHEM SYNTHESIS S.p.A. (IT) 1995-10-18 EP claimed
CN-115043703-B Purification method of high-purity methyl iodide for LED material 安徽泽升科技有限公司 2023-01-03 CN disclosed
CN-115504866-A Preparation method and application of 4-methoxy-2-naphthol 阜阳欣奕华制药科技有限公司 2022-12-23 CN disclosed
CN-113697945-B Biomembrane reactor for deep purification of sewage and operation method thereof 南京大学 2022-11-11 CN disclosed
US-5489316-A Process for making industrial organic solvents and hydrocarbons used as fuels ENICHEM SYNTHESIS S.P.A. (IT) 1996-02-06 US disclosed
EP-0677568-A1 Process for marking industrial organic solvents and hydrocarbons used as fuels ENICHEM SYNTHESIS S.p.A. (IT) 1995-10-18 EP disclosed