SCHEMBL4647848

SCHEMBL4647848

CC1=CC(=O)C(=O)c2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.68
ALDH1A1 P00352 3/20 0.68
MAPT P10636 3/20 0.68
HPGD P15428 3/20 0.68
MAPK1 P28482 3/20 0.68
CYP3A4 P08684 2/20 0.68
MEN1 O00255 2/20 0.68
LMNA P02545 2/20 0.68
TP53 P04637 2/20 0.68
BLM P54132 2/20 0.68
KMT2A Q03164 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
PLIN1 O60240 1/20 0.68
NR1I2 O75469 1/20 0.68
USP2 O75604 1/20 0.68
GSR P00390 1/20 0.68
CYP1A2 P05177 1/20 0.68
ADORA3 P0DMS8 1/20 0.68
GAA P10253 1/20 0.68
CYP2D6 P10635 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17861314 0.85 CDC25B (0.74) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL25970 0.81 MAPT (1.00) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL1364028 0.81 MAPT (1.00) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL29351164 0.81 MAPT (1.00) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL19356853 0.81 MAPT (1.00) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL3411128 0.79 MAPT (0.95) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL6680739 0.79 MAPT (0.95) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL9812440 0.79 MAPT (0.95) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL9807661 0.79 MAPT (0.95) CDC25BALDH1A1MAPTHPGDMAPK1
Menadione SCHEMBL9163371 0.79 MAPT (0.95) CDC25BALDH1A1MAPTHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11831017-B2 Redox flow battery electrolytes CMBLU ENERGY AG (DE) 2023-11-28 US disclosed
WO-2023189803-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
WO-2023189799-A1 SELF CROSS-LINKABLE POLYMER AND RESIST UNDERLAYER FILM-FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
US-11173146-B2 Selective activators of the intermediate conductance CA2+activated K+ channel KCa3.1 and their methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-11-16 US disclosed
US-20170056376-A1 SELECTIVE ACTIVATORS OF THE INTERMEDIATE CONDUCTANCE CA2+ACTIVATED K+ CHANNEL KCa3.1 AND THEIR METHODS OF USE UNIV CALIFORNIA (US) 2017-03-02 US disclosed
WO-2015164816-A2 SELECTIVE ACTIVATORS OF THE INTERMEDIATE CONDUCTANCE CA2+-ACTIVATED K+ CHANNEL KCA3.1 AND THEIR METHODS OF USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-10-29 WO disclosed
US-20090275664-A1 NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES PROGEN PHARMACEUTICALS, INC. 2009-11-05 US disclosed
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2009-02-12 US disclosed
US-20080290329-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2008-11-27 US disclosed
US-7420065-B2 Color-changing performance does not deteriorate even after used for long time and which is prevented from being unusable due to deposition of the coloring matter during storage IDEMITSU KOSAN CO., LTD. (JP) 2008-09-02 US disclosed
US-20070185338-A1 Benzo[c]carbazoles, benzo[b]naphthofurans, benzo[kl]xanthenes, and benzo[kl]acridines oxo- and tertiary amine-substituted; high luminescence intensities; heat resistance, light resistance, solubility, dispersibility in resist materials; emit light in solution and in solid state KOCHI UNIVERSITY (JP) 2007-08-09 US disclosed
US-7253207-B2 Quinones as disease therapies CELLGATE, INC. (US) 2007-08-07 US disclosed
EP-0514649-B1 Stabilization of aqueous solutions of watersoluble polymers in the presence of hydroxylamine CYTEC TECH CORP (US) 2000-10-25 EP disclosed
EP-0876368-A1 USE OF MONO- OR DIKETONE TETRACYCLIC DERIVATIVES, RESULTING NOVEL COMPOUNDS AND THERAPEUTICAL USE THEREOF LABORATOIRE INNOTHERA Société Anonyme (FR) 1998-11-11 EP disclosed
EP-0439585-B1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS MAG GEORG MAYRHOFER & CO OHG (AT) 1997-10-29 EP disclosed
WO-1997021709-A1 USE OF MONO- OR DIKETONE TETRACYCLIC DERIVATIVES, RESULTING NOVEL COMPOUNDS AND THERAPEUTICAL USE THEREOF LABORATOIRE INNOTHERA (FR) 1997-06-19 WO disclosed
US-5196478-A Polystyrene, assays EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1993-03-23 US disclosed
EP-0514649-A1 Stabilization of aqueous polymers in the presence of hydroxylamine CYTEC TECHNOLOGY CORP. (US) 1992-11-25 EP disclosed
EP-0439585-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. EPIPHARM ALLERGIE SERVICE (AT) 1991-08-07 EP disclosed
WO-1991002768-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1991-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11173146-B2 Selective activators of the intermediate conductance CA2+activated K+ channel KCa3.1 and their methods of use KCNN3, KCNN1, KCNN2 CDC25B 4313/4885ALDH1A1 3038/4885MAPT 4633/4885
US-20080290329-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS PBRM1, BICRA, PARG CDC25B 1260/4885ALDH1A1 4214/4885MAPT 190/4885
US-20070185338-A1 Benzo[c]carbazoles, benzo[b]naphthofurans, benzo[kl]xanthenes, and benzo[kl]acridines oxo- and tertiary amine-substituted; high luminescence intensities; heat resistance, light resistance, solubility, dispersibility in resist materials; emit light in solution and in solid state ABCG2, IK, XDH CDC25B 3025/4885ALDH1A1 601/4885MAPT 2105/4885
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS PBRM1, BICRA, PARG CDC25B 1260/4885ALDH1A1 4214/4885MAPT 190/4885
US-11831017-B2 Redox flow battery electrolytes GPX1, GPX4, NOX4 CDC25B 1271/4885ALDH1A1 260/4885MAPT 3707/4885
US-20170056376-A1 SELECTIVE ACTIVATORS OF THE INTERMEDIATE CONDUCTANCE CA2+ACTIVATED K+ CHANNEL KCa3.1 AND THEIR METHODS OF USE KCNN3, KCNN1, KCNN2 CDC25B 4313/4885ALDH1A1 3038/4885MAPT 4633/4885
US-20090275664-A1 NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES CTSB, CTSL, CTSV CDC25B 511/4885ALDH1A1 1038/4885MAPT 3032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.