SCHEMBL342409

SCHEMBL342409

O=C1C=C(O)c2ccccc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 1.00
MAPT P10636 4/20 1.00
HPGD P15428 2/20 1.00
ALDH1A1 P00352 1/20 1.00
CYP3A4 P08684 1/20 1.00
MAPK1 P28482 1/20 1.00
PTPN22 Q9Y2R2 1/20 1.00
PTPN1 P18031 8/20 0.59
KMT2A Q03164 4/20 0.59
POLB P06746 2/20 0.59
RECQL P46063 2/20 0.59
ATM Q13315 1/20 0.59
USP2 O75604 1/20 0.59
CTDSP1 Q9GZU7 1/20 0.59
PTPRC P08575 3/20 0.56
NSD2 O96028 2/20 0.56
HKDC1 Q2TB90 1/20 0.56
APAF1 O14727 2/20 0.54
TDP2 O95551 2/20 0.54
CDC25B P30305 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9915565 0.85 MAPT (0.74) KDM4EMAPTHPGDALDH1A1CYP3A4
Lawsone SCHEMBL16541 0.81 MAPT (0.68) KDM4EMAPTHPGDALDH1A1CYP3A4
Lawsone SCHEMBL6849999 0.81 MAPT (0.68) KDM4EMAPTHPGDALDH1A1CYP3A4
Lawsone SCHEMBL29350263 0.81 MAPT (0.68) KDM4EMAPTHPGDALDH1A1CYP3A4
Lawsone SCHEMBL5826345 0.81 MAPT (0.68) KDM4EMAPTHPGDALDH1A1CYP3A4
Lawsone SCHEMBL6052722 0.79 MAPT (0.65) KDM4EMAPTHPGDALDH1A1CYP3A4
Lawsone SCHEMBL6052709 0.79 MAPT (0.65) KDM4EMAPTHPGDALDH1A1CYP3A4
Lawsone SCHEMBL6052663 0.79 MAPT (0.65) KDM4EMAPTHPGDALDH1A1CYP3A4
SCHEMBL10445359 0.79 KDM4E (0.64) KDM4EMAPTHPGDALDH1A1CYP3A4
Lawsone SCHEMBL9136705 0.77 MAPT (0.63) KDM4EMAPTHPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694932-A2 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS Protomer Technologies Inc. (US) 2026-02-18 EP claimed
EP-4665832-A1 WELL PLATE FOR IMAGING The University of British Columbia (CA) 2025-12-24 EP claimed
WO-2024215876-A2 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS PROTOMER TECHNOLOGIES, INC. (US) 2024-10-17 WO claimed
US-12109297-B2 Process for treating keratin fibers employing an anhydride acrylic polymer in oily dispersion and an amine compound L'OREAL (FR) 2024-10-08 US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2024175043-A1 PYRIDOPYRIMIDINE DERIVATIVE AND USE THEREOF 广东东阳光药业股份有限公司 2024-08-29 WO claimed
WO-2024168428-A1 WELL PLATE FOR IMAGING THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-08-22 WO claimed
US-20240261210-A1 PROCESS FOR TREATING KERATIN FIBERS EMPLOYING AN ANHYDRIDE ACRYLIC POLYMER IN OILY DISPERSION AND AN AMINE COMPOUND L'OREAL (FR) 2024-08-08 US claimed
US-20240196889-A1 USE OF DI- AND TRICARBOXYLIC FATTY ACIDS IN THE PREVENTION OF BIOFILM FORMATION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-06-20 US claimed
CN-118202009-A Ink applicator 墨水盒墨水公司 2024-06-14 CN claimed
EP-4051242-A1 AMORPHOUS SOLID SUCCINYLATED 3-(FATTY ACID AMIDO)-2-HYDROXY-1-(PROTECTED HYDROXY)-PROPANE SALTS AND METHODS OF MAKING THE SAME GERON CORPORATION (US) 2022-09-07 EP claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
CN-114538616-A Method for enhancing denitrification performance and metabolic activity of aerobic denitrifying bacteria under low temperature condition 北京工业大学 2022-05-27 CN claimed
EP-3989915-A1 OILY DISPERSION COMPRISING A POLYMERIC PARTICLE AND A STABILIZER BEARING A C9-C22 ALKYL GROUP, AND PROCESS FOR TREATING KERATIN MATERIALS USING THE OILY DISPERSION L'OREAL (FR) 2022-05-04 EP claimed
US-20150159077-A1 Henna Corrosion Inhibitor for Acid in a Well HALLIBURTON ENERGY SERVICES, INC. 2015-06-11 US claimed
US-20140345871-A1 Henna Corrosion Inhibitor for Acid in a Well HALLIBURTON ENERGY SERVICES, INC. (US) 2014-11-27 US claimed
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2010-02-25 US claimed
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2008083974-A1 ACTIVE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2008067928-A1 UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE ISDIN S.A. (ES) 2008-06-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240196889-A1 USE OF DI- AND TRICARBOXYLIC FATTY ACIDS IN THE PREVENTION OF BIOFILM FORMATION FASN, HCAR2, HAO2 KDM4E 2508/4885MAPT 3742/4885HPGD 545/4885
US-12109297-B2 Process for treating keratin fibers employing an anhydride acrylic polymer in oily dispersion and an amine compound KRT18, AURKA, AURKC KDM4E 191/4885MAPT 1184/4885HPGD 2570/4885
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION UGT2B17, TACR2, UGT1A1 KDM4E 3725/4885MAPT 922/4885HPGD 601/4885
US-20240261210-A1 PROCESS FOR TREATING KERATIN FIBERS EMPLOYING AN ANHYDRIDE ACRYLIC POLYMER IN OILY DISPERSION AND AN AMINE COMPOUND KRT18, AURKA, AURKC KDM4E 191/4885MAPT 1184/4885HPGD 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.