SCHEMBL8994837

SCHEMBL8994837

c1ccc(N(c2ccc(-c3ccc(N(c4ccccc4)c4c5ccccc5cc5ccccc45)s3)s2)c2c3ccccc3cc3ccccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
APAF1 O14727 1/20 0.33
CASP3 P42574 1/20 0.33
CASP6 P55212 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
NQO1 P15559 1/20 0.32
NQO2 P16083 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994833 0.81 TRPM4 (0.33) APPALDH1A1HSD17B10KDM4EMEN1
SCHEMBL29904929 0.80 ALDH1A1 (0.43) ALDH1A1HSD17B10KDM4EMEN1CYP1A2
SCHEMBL2757438 0.80 ALDH1A1 (0.43) ALDH1A1HSD17B10KDM4EMEN1CYP1A2
Benzene SCHEMBL4542530 0.80 ALDH1A1 (0.43) ALDH1A1HSD17B10KDM4EMEN1CYP1A2
SCHEMBL6123825 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10KDM4EMEN1CYP1A2
SCHEMBL8994693 0.78 APP (0.43) APPALDH1A1KDM4EMEN1CYP1A2
SCHEMBL8994816 0.77 SIGMAR1 (0.41) APPALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL13720783 0.77 ALDH1A1 (0.45) ALDH1A1HSD17B10KDM4EMEN1CYP1A2
SCHEMBL13720439 0.77 ALDH1A1 (0.45) ALDH1A1HSD17B10KDM4EMEN1CYP1A2
SCHEMBL6123822 0.77 ALDH1A1 (0.45) ALDH1A1HSD17B10KDM4EMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed