SCHEMBL8994833

SCHEMBL8994833

c1ccc(N(c2ccc(-c3ccc(N(c4ccccc4)c4cc5ccccc5c5ccccc45)s3)s2)c2cc3ccccc3c3ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.33
APP P05067 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
HSD17B10 Q99714 1/20 0.32
APAF1 O14727 1/20 0.31
CASP3 P42574 1/20 0.31
CASP6 P55212 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
HPRT1 P00492 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994883 0.90 HPRT1 (0.39) APPALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL16595581 0.84 APP (0.33) APPCYP1B1
SCHEMBL9888888 0.82 TRPM4 (0.43) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL6287052 0.82 TRPM4 (0.43) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL8994816 0.81 SIGMAR1 (0.41) APPALDH1A1CYP1B1HSD17B10KDM4E
SCHEMBL8994837 0.81 APP (0.34) APPALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL14069628 0.80 TRPM4 (0.42) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL13271325 0.79 TRPM4 (0.41) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL12333196 0.79 ALDH1A1 (0.42) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL15730661 0.79 ALDH1A1 (0.42) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed