Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994846 | 1.00 | LTB4R (0.53) | LTB4RGAARAB9ATP53NPC1 | |
| SCHEMBL8995041 | 0.88 | LTB4R (0.54) | LTB4RGAARAB9ATP53NPC1 | |
| SCHEMBL8994902 | 0.88 | LTB4R (0.72) | LTB4RLMNAMAPTLTB4R2TSHR | |
| SCHEMBL8994895 | 0.88 | LTB4R (0.72) | LTB4RLMNAMAPTLTB4R2TSHR | |
| SCHEMBL8994916 | 0.88 | LTB4R (0.46) | LTB4RGAARAB9ATP53NPC1 | |
| SCHEMBL8995040 | 0.88 | LTB4R (0.46) | LTB4RGAARAB9ATP53NPC1 | |
| SCHEMBL8994922 | 0.88 | LTB4R (0.46) | LTB4RGAARAB9ATP53NPC1 | |
| SCHEMBL8994847 | 0.87 | LTB4R (0.46) | LTB4RGAARAB9ATP53NPC1 | |
| SCHEMBL8748256 | 0.85 | GAA (0.63) | LTB4RGAARAB9ATP53NPC1 | |
| SCHEMBL8748258 | 0.85 | GAA (0.63) | LTB4RGAARAB9ATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5451700-A | Leukotriene inhibitors | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |