SCHEMBL8994988

SCHEMBL8994988

c1ccc(N(c2ccccc2)c2ccc(-c3ccc(-c4ccc(N(c5ccccc5)c5ccccc5)s4)s3)s2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.46
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALOX15 P16050 1/20 0.34
MEN1 O00255 1/20 0.32
CRHBP P24387 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
CRHR2 Q13324 1/20 0.32
TLR9 Q9NR96 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13707363 1.00 APP (0.46) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL8994693 0.98 APP (0.43) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL13707364 0.90 APP (0.51) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL3365672 0.90 APP (0.41) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL8994780 0.88 APP (0.49) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL8995109 0.88 APP (0.49) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL21976554 0.87 APP (0.47) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL18193947 0.86 APP (0.55) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL8994673 0.85 ALDH1A1 (0.44) APPALDH1A1MAPTTDP1L3MBTL1
SCHEMBL8994805 0.85 APP (0.46) APPALDH1A1MAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed