SCHEMBL3365672

SCHEMBL3365672

Brc1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)s3)s2)s1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.41
MAPT P10636 6/20 0.38
RXFP1 Q9HBX9 4/20 0.38
NPC1 O15118 3/20 0.38
ALDH1A1 P00352 3/20 0.38
TP53 P04637 3/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HPGD P15428 1/20 0.38
PPARG P37231 1/20 0.38
NCOA2 Q15596 1/20 0.38
NCOA1 Q15788 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38
ALOX12 P18054 2/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13707363 0.90 APP (0.46) APPMAPTNPC1ALDH1A1RAB9A
SCHEMBL8994988 0.90 APP (0.46) APPMAPTNPC1ALDH1A1RAB9A
SCHEMBL16282227 0.88 ALDH1A1 (0.37) APPMAPTRXFP1NPC1ALDH1A1
SCHEMBL8994693 0.88 APP (0.43) APPMAPTALDH1A1KDM4EL3MBTL1
SCHEMBL14236086 0.82 ALDH1A1 (0.35) APPMAPTRXFP1NPC1ALDH1A1
SCHEMBL3368635 0.82 SIGMAR1 (0.36) APPMAPTRXFP1NPC1ALDH1A1
SCHEMBL3364842 0.82 ALDH1A1 (0.33) MAPTRXFP1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL13707364 0.81 APP (0.51) APPMAPTNPC1ALDH1A1RAB9A
SCHEMBL8994780 0.79 APP (0.49) APPMAPTNPC1ALDH1A1RAB9A
SCHEMBL8995109 0.79 APP (0.49) APPMAPTNPC1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL CRY1, DSG1, CRY2 APP 2553/4885MAPT 4399/4885RXFP1 4797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.