Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.68 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994893 | 0.88 | LTB4R (0.74) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL8994891 | 0.85 | LTB4R (0.75) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL8747955 | 0.85 | LTB4R (0.78) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL8747956 | 0.85 | LTB4R (0.78) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL8748238 | 0.85 | LTB4R (0.78) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL8748241 | 0.85 | LTB4R (0.78) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL8747965 | 0.84 | LTB4R (0.76) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL8747967 | 0.84 | LTB4R (0.76) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL6138115 | 0.84 | LTB4R (0.74) | LTB4RLTB4R2PLA2G4BMAPTLMNA | |
| SCHEMBL8994930 | 0.83 | LTB4R (0.75) | LTB4RLTB4R2PLA2G4BMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |