Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LATS1 | O95835 | 1/20 | 0.43 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899501 | 1.00 | ALDH1A1 (0.43) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL27574491 | 0.84 | NPC1 (0.41) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL6325960 | 0.84 | CHRNB2 (0.65) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL6325966 | 0.84 | CHRNB2 (0.65) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL27552209 | 0.78 | NPC1 (0.44) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL23727595 | 0.78 | NPC1 (0.58) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL23727593 | 0.78 | NPC1 (0.58) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL27579070 | 0.74 | NPC1 (0.41) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL27939399 | 0.72 | NR1I3 (0.43) | ALDH1A1NPC1JAK2RAB9APAX8 | |
| SCHEMBL903016 | 0.72 | ALDH1A1 (0.40) | ALDH1A1HTTSMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |