Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899436 | 0.83 | PDE4D (0.39) | ALDH1A1KDM4EGAANPSR1LMNA | |
| SCHEMBL899381 | 0.77 | MAPT (0.41) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL899307 | 0.74 | MAPT (0.46) | ALDH1A1NPSR1LMNAHPGDMAPT | |
| SCHEMBL899306 | 0.74 | MAPT (0.46) | ALDH1A1NPSR1LMNAHPGDMAPT | |
| SCHEMBL898806 | 0.73 | GRM5 (0.34) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL898805 | 0.73 | GRM5 (0.34) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL899501 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMAPTMAPK1 | |
| SCHEMBL899502 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMAPTMAPK1 | |
| SCHEMBL898781 | 0.72 | ROCK2 (0.41) | NPSR1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL898780 | 0.72 | ROCK2 (0.41) | NPSR1LMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |