Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8995059 | 0.99 | THRB (0.43) | THRBTHRALTB4RCA1CA2 | |
| Hydrochloric Acid SCHEMBL9700654 | 0.89 | THRB (0.40) | THRBTHRALTB4RCA1CA2 | |
| SCHEMBL7711188 | 0.88 | MAOB (0.48) | LTB4RLTB4R2MAOBMAOAALB | |
| Hydrochloric Acid SCHEMBL8995085 | 0.88 | MAOB (0.47) | LTB4RLTB4R2MAOBMAOAALB | |
| Hydrochloric Acid SCHEMBL8995056 | 0.88 | LTB4R (0.44) | THRBTHRALTB4RLTB4R2MEN1 | |
| Hydrochloric Acid SCHEMBL8995058 | 0.88 | LTB4R (0.42) | THRBTHRALTB4RCA1CA2 | |
| SCHEMBL8995022 | 0.86 | CA1 (0.41) | THRBTHRACA1CA2CA9 | |
| Acetic Acid SCHEMBL7716017 | 0.86 | MAOB (0.46) | LTB4RLTB4R2MAOBMAOAALB | |
| Hydrochloric Acid SCHEMBL8994966 | 0.86 | LTB4R (0.49) | THRBTHRALTB4RLTB4R2MEN1 | |
| Hydrochloric Acid SCHEMBL8994900 | 0.86 | CA1 (0.41) | THRBTHRACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |