Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 6/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8994900 | 0.99 | CA1 (0.41) | CA1CA2CA9CA12THRB | |
| Hydrochloric Acid SCHEMBL9141519 | 0.89 | MAOB (0.43) | ALBAPPMAOAMAOB | |
| SCHEMBL8995037 | 0.86 | THRB (0.43) | CA1CA2CA9CA12THRB | |
| Hydrochloric Acid SCHEMBL8591156 | 0.86 | ALDH1A1 (0.41) | TRPM8ALBFAAH | |
| Hydrochloric Acid SCHEMBL8995059 | 0.85 | THRB (0.43) | CA1CA2CA9CA12THRB | |
| SCHEMBL9699610 | 0.85 | MLYCD (0.46) | TRPM8FAAH | |
| SCHEMBL8748028 | 0.83 | RAB9A (0.47) | THRBTHRANR1H4SMN1; SMN2 | |
| SCHEMBL8748025 | 0.83 | RAB9A (0.47) | THRBTHRANR1H4SMN1; SMN2 | |
| SCHEMBL8995004 | 0.83 | LTB4R (0.50) | MAOA | |
| SCHEMBL8748089 | 0.83 | THRA (0.42) | THRBTHRANR1H4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |