Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995081 | 0.91 | MAOB (0.45) | MAOBMAOAPPARDLTB4R | |
| SCHEMBL8994849 | 0.90 | THRB (0.44) | MAOBLTB4R | |
| SCHEMBL8994916 | 0.81 | LTB4R (0.46) | MAOBMAOAPPARDLTB4R | |
| SCHEMBL8994922 | 0.81 | LTB4R (0.46) | MAOBMAOAPPARDLTB4R | |
| SCHEMBL8995040 | 0.81 | LTB4R (0.46) | MAOBMAOAPPARDLTB4R | |
| SCHEMBL8994933 | 0.81 | THRB (0.43) | MAOBLTB4R | |
| SCHEMBL8591163 | 0.78 | MAOB (0.47) | MAOBMAOAPPARDLTB4R | |
| SCHEMBL9146446 | 0.77 | MAOB (0.41) | MAOBMAOALTB4R | |
| SCHEMBL8590612 | 0.77 | LTB4R (0.42) | MAOBPPARDLTB4R | |
| SCHEMBL8747961 | 0.76 | GAA (0.53) | MAOBMAOAPPARDLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | claimed |
| US-5451700-A | Leukotriene inhibitors | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | claimed |