Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994849 | 0.91 | THRB (0.44) | THRBTHRALTB4RMEN1PKM | |
| SCHEMBL8995081 | 0.90 | MAOB (0.45) | LTB4RMAOB | |
| SCHEMBL8995015 | 0.87 | ATM (0.40) | THRBTHRAMEN1KMT2AATM | |
| SCHEMBL8590612 | 0.85 | LTB4R (0.42) | THRBTHRALTB4RMEN1PKM | |
| SCHEMBL8995047 | 0.85 | LTB4R (0.47) | LTB4RITGB3ITGA2BLTB4R2SRD5A2 | |
| SCHEMBL8590372 | 0.83 | PPARA (0.40) | LTB4R | |
| SCHEMBL8593369 | 0.82 | FFAR1 (0.40) | LTB4R | |
| SCHEMBL8593372 | 0.81 | LTB4R (0.35) | THRBTHRALTB4RMEN1PKM | |
| SCHEMBL8994927 | 0.81 | LTB4R (0.47) | THRBTHRALTB4RMEN1PKM | |
| SCHEMBL8995044 | 0.81 | MAOB (0.44) | LTB4RMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |