Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995000 | 0.71 | TLR8 (0.38) | PPARAL3MBTL1KMT2A | |
| SCHEMBL5734668 | 0.70 | PPARA (0.33) | PPARAL3MBTL1KMT2A | |
| SCHEMBL285375 | 0.69 | GCGR (0.40) | — | |
| SCHEMBL17514350 | 0.68 | MLYCD (0.40) | PPARAALDH1A1KMT2A | |
| SCHEMBL4564307 | 0.67 | GAA (0.41) | PPARAPPARGALDH1A1NPC1RAB9A | |
| SCHEMBL27853904 | 0.66 | ALOX5 (0.47) | ALOX5PPARAPPARGALDH1A1PTGS2 | |
| SCHEMBL28212760 | 0.65 | TYR (0.36) | PPARAALDH1A1LMNAKMT2APTGS2 | |
| SCHEMBL109295 | 0.64 | GCGR (0.35) | HTTL3MBTL1NPC1RAB9A | |
| SCHEMBL15255830 | 0.63 | TLR8 (0.34) | ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL31693622 | 0.61 | CA12 (0.40) | PPARAALDH1A1HTTKMT2AFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725777-A1 | PROCESS FOR PREPARING 3,4-DIARYL-5-ISOXAZOLYL ACETIC ACID DERIVATIVES | F. JOH. KWIZDA GESELLSCHAFT M.B.H. (AT) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995011888-A1 | PROCESS FOR PREPARING 3,4-DIARYL-5-ISOXAZOLYL ACETIC ACID DERIVATIVES | F. JOH. KWIZDA GESELLSCHAFT M.B.H. (AT) | 1995-05-04 | — | — | WO | disclosed |