Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209831 | 0.81 | HRH3 (0.58) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL31146852 | 0.80 | CHRNB2 (0.50) | ALDH1A1SMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL5692377 | 0.79 | HRH3 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL272824 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL5693237 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL11734984 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL342467 | 0.77 | NQO1 (0.64) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL8765685 | 0.77 | ESR1 (0.41) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL851166 | 0.76 | ALDH1A1 (0.66) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL8754251 | 0.76 | ALDH1A1 (0.56) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496844-A | Indole derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0639567-A1 | INDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-22 | — | — | EP | disclosed |